Lillehoj Research Group
Our group aims to develop innovative microfluidic technologies for broad applications in medical diagnostics, cell-based therapeutics and global health. Our research is highly interdisciplinary and combines multiple specialties, including micro-electrical-mechanical systems (MEMS), microfluidics, biosensors, nanotechnology, analytical chemistry, and microelectronics.
Latest News
3/6/2025: Our work on developing a Tc24-based magneto-immunoassay for the detection of Chagas disease is published in The Journal of Infectious Diseases!
Our paper titled "Rapid High-Sensitivity Detection of Antibodies to Trypanosoma cruzi With a Recombinant Tc24 Antigen-Based Magneto-Immunoassay: A Pilot Study" is published in The Journal of Infectious Diseases!
2/28/2025: Our work on developing a AI-enabled microfluidic cytometer is published in Microsystems & Nanoengineering!
Our paper titled “Artificial intelligence-enabled microfluidic cytometer using gravity-driven slug flow for rapid CD4+ T cell quantification in whole blood" is published in Nature Microsystems & Nanoengineering!
2/27/2025: Our work on developing a rapid laser ablation-based technique for fabricating polymer microwell arrays is published in Lab on a Chip!
Our paper titled “Rapid laser ablation-based fabrication of high-density polymer microwell arrays for high-throughput cellular studies" is published in Lab on a Chip!
2/5/2025: Our work on developing a MN-based technique for high volume sampling of dermal ISF is published in Bio-protocol!
Our paper titled “Rapid Sampling of Large Quantities of Interstitial Fluid from Human Skin Using Microneedles and a Vacuum-assisted Skin Patch” is published in Bio-protocol!
12/26/2024: Our work on machine learning-enabled interpretation of CRISPR-Cas-based LFA test results is published in Sensors & Diagnostics!
Our paper titled “Rapid and automated interpretation of CRISPR-Cas13-based lateral flow assay test results using machine learning” is published in ACS Sensors!
10/25/2024: Our work on developing a skin patch for rapid protein detection in human ISF is published in ACS Sensors!
Our paper titled “Lateral Flow-Based Skin Patch for Rapid Detection of Protein Biomarkers in Human Dermal Interstitial Fluid” is published in ACS Sensors!