Publications
E.C. Wilkirson, D. Li, P.B. Lillehoj, “Lateral Flow-Based Skin Patch for Rapid Detection of Protein Biomarkers in Human Dermal Interstitial Fluid,” ACS Sensors, 9:5792-5801, 2024.
E.C. Wilkirson, P.B. Lillehoj, “Highly Wicking Cellulose Microneedles for Rapid Sampling and Transport of Dermal Interstitial Fluid,” Proceedings of the 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2024), in press.
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D.D. Dixit, K.L. Singampalli, A. Montoya, A. Reuben, P.B. Lillehoj, “AC Electrothermal Flow-Enhanced Screening of High-Affinity Anti-Tumor T Cells,” Proceedings of the 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2024), in press.
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B. Utzinger, D.D. Dixit, P.B. Lillehoj, “Microfluidic finger-actuated mixer for ultrasensitive electrochemical measurements of protein biomarkers for point-of-care testing,” Lab on a Chip, 24:3802-3809, 2024.
X. Jiang, E.C. Wilkirson, A.O. Bailey, W.K. Russell, P.B. Lillehoj, “Microneedle-based sampling of dermal interstitial fluid using a vacuum-assisted skin patch,” Cell Reports Physical Science, 5(6):101975, 2024.
K.L. Singampalli, C. Neal – Harris, C. Yee, J.S. Lin, P.B. Lillehoj, “Highly Reusable Electrochemical Immunosensor for Ultrasensitive Protein Detection,” Advanced Sensor Research, 2400004, DOI: 10.1002/adsr.202400004, 2024.
J. Li, A.M. Saidi, K. Seydel, P.B. Lillehoj, “Rapid diagnosis and prognosis of malaria infection using a microfluidic point-of-care immunoassay,” Biosensors and Bioelectronics, 250(15):116091, 2024.
E.C. Wilkirson, Y. Gong, W. Li, P.B. Lillehoj. Wearable Impedance Sensor for Wireless Measurements of Protein Biomarkers in Dermal Interstitial Fluid. Proceedings of the 2024 IEEE 37th International Conference on Micro Electro Mechanical Systems (MEMS), 371-374.
E.C. Wilkirson, K.L. Singampalli, J. Li, D.D. Dixit, X. Jiang, D.H. Gonzalez, P.B. Lillehoj, “Affinity-based electrochemical sensors for biomolecular detection in whole blood,” Analytical and Bioanalytical Chemistry, 415(18):3983-4002, 2023.
K.L. Singampalli, J. Li, P.B. Lillehoj, “Rapid magneto-enzyme-linked immunosorbent assay for ultrasensitive protein detection,” Analytica Chimica Acta, 1225:340246, 2022.
N. Dutta, P.B. Lillehoj, P. Estrela, G. Dutta, “Electrochemical Biosensors for Cytokine Profiling: Recent Advancements and Possibilities in the Near Future,” Biosensors, 11(3), 94, 2021.
J. Li, P.B. Lillehoj. AC electrothermal flow-enhanced magneto-immunosensor for rapid protein quantification in blood. Proceedings of the 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2021), 1457-1458.
X. Jiang, P.B. Lillehoj, “Microneedle-based skin patch for blood-free rapid diagnostic testing,” Microsystems & Nanoengineering, 6:96, 2020.
H. Tsutsui, P.B. Lillehoj “Flexible analytical devices for point-of-care testing,” SLAS Technology, 25:6-8, 2020. 
J. Li, P.B. Lillehoj, “AC electrothermal flow-enhanced, label-free immunosensor for rapid electrochemical sensing,” Proceedings of the 2020 IEEE 15th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), 554-558.
X. Jiang, P.B. Lillehoj, “A microneedle-based lateral flow immunoassay for rapid protein detection,” Proceedings of the 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2019), ISBN (electronic): 978-1-7334190-0-0, 650-651.
G. Dutta, P.B. Lillehoj, “Wash-free, label-free immunoassay for rapid electrochemical detection of PfHRP2 in whole blood samples,” Scientific Reports, 8:17129, 2018.
S. Parsnejad, Y. Gtat, T.Y. Lin, X. Liu, P.B. Lillehoj, A. Mason, “Self-ranging thumb-sized multichannel electrochemical instrument for global wearable point-of-care sensing,” Proceedings of the 2018 IEEE 61st International Midwest Symposium on Circuits and Systems (MWSCAS), 57-60.
G. Dutta, P.B. Lillehoj, “An ultrasensitive enzyme-free electrochemical immunosensor based on redox cycling amplification using methylene blue,” Analyst, 142, 3492-3499, 2017.
T.Y. Lin, T.T. Pfeiffer, P.B. Lillehoj, “Stability of UV/ozone-treated thermoplastics under different storage conditions for microfluidic analytical devices,” RSC Advances, 7, 37374-37379, 2017.
X. Liu, P.B. Lillehoj, “Embroidered electrochemical sensors on gauze for rapid quantification of wound biomarkers,” Biosensors and Bioelectronics, 98, 189-194, 2017.
T.Y. Lin, T. Do, P. Kwon, P.B. Lillehoj, “3D printed metal molds for hot embossing plastic microfluidic devices,” Lab on a Chip, 17, 241-247, 2017.
G. Dutta, S. Nagarajan, L.J. Lapidus, P.B. Lillehoj, “Enzyme-free electrochemical immunosensor based on methylene blue and the electro-oxidation of hydrazine on Pt nanoparticles,” Biosensors and Bioelectronics, 92, 372-377, 2017.
T.Y. Lin, S. Parsenjad, L. Tu, T.T. Pfeiffer, A.J. Mason, G. Xing, P.B. Lillehoj, “Finger-powered microfluidic electrochemical assay for point-of-care testing,” Proceedings of the 2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), 313-317.
S. Parsnejad, T.Y. Lin, Y. Hu, H. Wan, E. Ashoori, P. Lillehoj, A. Mason, “Compact, adaptive, multichannel electrochemical instrument for point-of-care sensing,” Proceedings of the 2016 IEEE Healthcare Innovation Point-Of-Care Technologies Conference (HI-POCT), 48.
T.Y. Lin, P.B. Lillehoj, “Stability of UV/Ozone treatment of plastics for capillary-driven microfluidics,” Solid-State Sensors, Actuators and Microsystems Workshop (Hilton Head 2016), 185-188.
X. Liu, P.B. Lillehoj, “Textile-based electrochemical sensors using embroidered electrodes,” Solid-State Sensors, Actuators and Microsystems Workshop (Hilton Head 2016), 43-46.
C. Wu, P.B. Lillehoj, P. Wang, “Bioanalytical and chemical sensors using living taste, olfactory, and neural cells and tissues: a short review,” Analyst, 140, 7048-7061, 2015.
X. Liu, P.B. Lillehoj, “Electrochemical detection in stacked paper networks,” Journal of Laboratory Automation, 20, 506-510, 2015.
X. Liu, P.B. Lillehoj, “A liquid-activated textile battery for wearable biosensors,” Journal of Physics: Conference Series, 2015, 660(1):012063.
X. Liu, T.Y. Lin, P.B. Lillehoj, “Smartphones for cell and biomolecular detection,” Annals of Biomedical Engineering, 42, 2205-2217, 2014.
P.B. Lillehoj, C.W. Kaplan, J. He, W. Shi, C.-M. Ho, “Rapid, electrical impedance detection of bacterial pathogens using immobilized antimicrobial peptides,” Journal of Laboratory Automation, 19, 42-49, 2014.
P.B. Lillehoj, M.-C. Huang, N. Truong, C.-M. Ho, “Rapid electrochemical detection on a mobile phone,” Lab on a Chip, 13, 2950-2955, 2013.
J.T. Wen, C.-M. Ho, P.B. Lillehoj, “Coffee ring aptasensor for rapid protein detection,” Langmuir, 29, 8440-8446, 2013.
P.B. Lillehoj, M.C. Huang, C.M. Ho, “A handheld, cell phone-based electrochemical biodetector,” Proceedings of the 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS), 53-56.
P.B. Lillehoj, C. Kaplan, J. He, W. Shi, C.M. Ho, “A microfluidic biosensor for multiplexed detection of bacterial pathogens,” Proceedings of the 2012 IEEE 6th International Conference on Nano/Molecular Medicine and Engineering (NANOMED), 117-121.
C. Wu, P.B. Lillehoj, L. Sabet, P. Wang, C.M. Ho, “Ultrasonication on a microfluidic chip to lyse single and multiple Pseudo-nitzschia for marine biotoxin analysis,” Biotechnology Journal, 6, 150-155, 2011.
F. Wei, P.B. Lillehoj, C.M. Ho, “DNA diagnostics: nanotechnology-enhanced electrochemical detection of nucleic acids,” Pediatric Research, 67, 458-468, 2010.
P.B. Lillehoj, F. Wei, C.M. Ho, “A self-pumping lab-on-a-chip for rapid detection of botulinum toxin,” Lab on a Chip, 10, 2265-2270, 2010.
P.B. Lillehoj, C.M. Ho, “A long-term, stable hydrophilic poly(dimethylsiloxane) coating for capillary-based pumping,” Proceedings of the 2010 IEEE 23rd International Conference on Micro Electro Mechanical Systems (MEMS), 1063-1066.
C. Wu, P.B. Lillehoj, P. Wang, C.M. Ho, “A microfluidic device for single and small population cell trapping and lysis of Pseudo-nitzschia,” Proceedings of the 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), 975-978.
P. Lillehoj, N. Li, H. Tsutsui, C.M. Ho, “A compact microfluidic continuous flow separator for particle and cell sorting,” Proceedings of the 2008 IEEE 21st International Conference on Micro Electro Mechanical Systems (MEMS), 292-295.Patents
“Electrothermal flow-enhanced electrochemical magneto-immunosensor” U.S. Provisional Patent Application US20230384297A1.
Inventors: P.B. Lillehoj, J. Li
“Embroidered electrochemical biosensors and related methods” U.S. Patent US11867655B2; International Patent WO2017189966A1.
Inventors: P.B. Lillehoj, X. Liu
“Handheld cell phone-based electrochemical biodetector” U.S. Provisional Patent 61/746,343.
Inventors: P.B. Lillehoj, M.C. Huang
“A cell phone SIM card-based biosensor” U.S. Provisional Patent 61/490,330.
Inventors: P.B. Lillehoj
“A self-pumping Lab-on-a-chip for rapid detection of botulinum toxin” U.S. Provisional Patent 61/295,571.
Inventors: P.B. Lillehoj, F. Wei